The bearing in it does need to be "engaged" at least (in run time hours) for at least a minute to seat the bearing in its gear after about 10 hours of run time - idle or drive or whatever time - that is RUN time, when the engines is started so is its timer - until the motor shuts off.
The AC also runs when you use the Defroster or anytime the windshield Icon in the Climate control - is on. So pulling the Fuse is the only way to keep the clutch of the compressor from engaging when there is no oil or refrigerant with oil - to circulate.
This clutch engage process lets the shaft turn with the bearing engaged or seated so this it's not the only thing rotating - the shaft it sits in has the roller bearings that turn with that main bearing - drawing out it's lube into the bearing together so it will "align and engage" properly next time - it's a needed process else the solenoid / magnet when it tries pulling the clutch in, won't mesh - then that is where the failure occurs. The seat ran dry.
The above comes from DIRECT experience from my own vehicles - in trying to save fuel costs and money by skipping the AC - that is where I made an epic fail in both the compressor, allowing it to run dry as in seized - and the water pump was taken out with it.
In some motors the AC delete just means you have to remove the part and use a different size smaller belt and, in a way, - makes everything in what is left of the serpentine - work more efficiently. Ford doesn't let you do that, which is a shame because these motors would last a really long - long time if such things like the AC was taken off and let the end user just own a vehicle to drive with just the basics - at in my life work. I never was "Forced" to use AC - until I had a Toyota-one seize on me in the middle of a traffic snarl - hard lesson but hey, 209,000 miles on the ODO - I guess it was worth it.
In GM Toyota and Chrysler - even KIA (At least the ones I owned) - all the AC units could get pulled and left out - you just ran a different belt to make all the rest work in the system.
Length of time? Enough to lubricate the seals - it Has to run for at least one minute - even then the lifetime is still finite - so with the compressor costing so much in Australian currency - it may be better to try and use a rebuilt unit or run with a AC delete "dummy" roller as
@scotman mentions.
You can disconnect the fuse, but the bearing will eventually run dry - so don't overlook this...
Thanks!